Tag Archives: Cystic

Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Due to this mutation, the CFTR protein doesn’t embed in cell membranes to form a channel for chlorine ions the way it should. As a result, mucus-producing cells secrete a thicker-than-normal mucus that can create blockages in the lungs and… Read More »

Cystic fibrosis drugs rejected for use by NHS in Scotland

Two “life-changing” cystic fibrosis drugs have been rejected for routine use by the NHS in Scotland. The Scottish Medicines Consortium (SMC) said there were uncertainties about the long-term health benefits of Orkambi and Symkevi in relation to their costs. Manufacturer Vertex and the Scottish government are now working “as a matter of urgency” to find… Read More »