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Basic Fact Sheet Detailed Version. Basic fact sheets are presented in plain language for individuals with general questions about sexually transmitted diseases. The content here can be syndicated added to your web site. Genital herpes is an STD caused by two types of viruses. Oral herpes is usually caused by HSV-1 and can result in cold sores or fever blisters on or around the mouth. However, most people do not have any symptoms. Most people with oral herpes were infected during childhood or young adulthood from non-sexual contact with saliva. Oral herpes caused by HSV-1 can be spread from the mouth to the genitals through oral sex.